Publikationen

 

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2025

Schierz, A. K.; Rößler, G.; Schneider, J. P.; Tschanz, S. A.; Werlein, C.; Jonigk, D. D.; Schipke, J.; Mühlfeld, C. Distribution and Volume of Mitochondria in Alveolar Epithelial Type 1 Cells in Infant and Adult Human Lungs. Histochemistry and Cell Biology 2025, 163 (1), 7.

2024

Rößler, G.; Labode, J.; Schipke, J.; Tschanz, S. A.; Mühlfeld, C. Three-Dimensional Characteristics of the Alveolar Capillary Network in Infant and Adult Human Lungs. Pediatric Research 2024.

2023

Schneiter, M. M.; Tschanz, S. A.; Escher, A. E.; Müller, L. L.; Frenz, M. The Cilialyzer - A Freely Available Open-Source Software for the Analysis of Mucociliary Activity in Respiratory Cells. Computer methods and programs in biomedicine 2023, 241, 107744.

Escher, A. E.; Kieninger, E.; De Groof, S.; Savas, S. T.; Schneiter, M. M.; Tschanz, S. A.; Frenz, M.; Latzin, P.; Casaulta, C.; Müller, L. L. In Vitro Effect of Combined Hypertonic Saline and Salbutamol on Ciliary Beating Frequency and Mucociliary Transport in Human Nasal Epithelial Cells of Healthy Volunteers and Patients With Cystic Fibrosis. Journal of aerosol medicine and pulmonary drug delivery 2023, 36 (4), 171-180.

2022

Fränkl, S.; Simon, Q.; Yucel, Y.; Gupta, N.; Wittwer, V. V.; Frueh, B. E.; Tschanz, S. A. Impact of Cerebral Hypoperfusion-Reperfusion on Optic Nerve Integrity and Visual Function in the DBA 2J Mouse Model of Glaucoma. BMJ open ophthalmology 2022, 7 (1).

2021

Nussbaumer, M.; Kieninger, E.; Tschanz, S. A.; Savas, S. T.; Casaulta, C.; Goutaki, M.; Blanchon, S.; Jung, A.; Regamey, N.; Kühni, C.; Latzin, P.; Müller, L. L. Diagnosis of Primary Ciliary Dyskinesia: Discrepancy According to Different Algorithms. ERJ Open Research 2021, 7 (4), 00353-2021.

Müller, L. L.; Savas, S. T.; Tschanz, S. A.; Stokes-Luginbühl, A.; Escher, A. E.; Nussbaumer, M.; Bullo, M.; Kühni, C.; Blanchon, S.; Jung, A.; Regamey, N.; Haenni, B.; Schneiter, M. M.; Ingold, J.; Kieninger, E.; Casaulta, C.; Latzin, P. A Comprehensive Approach for the Diagnosis of Primary Ciliary Dyskinesia—Experiences from the First 100 Patients of the PCD-UNIBE Diagnostic Center. Diagnostics 2021, 11 (9), 1540.

Schneiter, M. M.; Halm, S.; Odriozola Quesada, A.; Mogel-Allemann, H. M.; Rička, J.; Stoffel, M. H.; Zuber, B.; Frenz, M.; Tschanz, S. A. Multi-Scale Alignment of Respiratory Cilia and Its Relation to Mucociliary Function. Journal of structural biology 2021, 213 (1), 107680.

Haberthür, D.; Yao, E.; Barré, S.; Cremona, T. P.; Tschanz, S. A.; Schittny, J. Pulmonary Acini Exhibit Complex Changes During Postnatal Rat Lung Development. PLoS ONE 2021, 16 (11), e0257349.

Sabatasso, S.; Fernandez Palomo, C. G.; Hlushchuk, R.; Fazzari, J. M.; Tschanz, S. A.; Pellicioli, P.; Krisch, M.; Laissue, J.; Djonov, V. G. Transient and Efficient Vascular Permeability Window for Adjuvant Drug Delivery Triggered by Microbeam Radiation. Cancers 2021, 13 (9).

2020

Wang, L.; Dorn, P.; Simillion, C.; Froment, L.; Berezowska, S. A.; Tschanz, S. A.; Haenni, B.; Blank, F.; Wotzkow Alvarez, C.; Peng, R.-W.; Marti, T.; Bode, P. K.; Moehrlen, U.; Schmid, R.; Hall, S. EpCAM+CD73+ Mark Epithelial Progenitor Cells in Postnatal Human Lung and Is Associated With Pathogenesis of Pulmonary Disease Including Lung Adenocarcinoma. American journal of physiology - lung cellular and molecular physiology 2020, 319 (5), L794-L809.

Halm, S.; Fairhurst, P. G. A. P.; Tschanz, S. A.; Wieland, F. A. M.; Djonov, V. G.; Krause, F. Effect of Lateral Sliding Calcaneus Osteotomy on Tarsal Tunnel Pressure. Foot & Ankle Orthopaedics 2020, 5 (3), 247301142093101.

Beyeler, S. M.; Steiner, S.; Wotzkow, C.; Tschanz, S. A.; Adhanom Sengal, A.; Wick, P.; Haenni, B.; Alves, M.; von Garnier, C.; Blank, F. Multi-Walled Carbon Nanotubes Activate and Shift Polarization of Pulmonary Macrophages and Dendritic Cells in an in Vivo Model of Chronic Obstructive Lung Disease. Nanotoxicology 2020, 14 (1), 77-96.

Baum, O.; Bernd, J.; Becker, S.; Odriozola Quesada, A.; Zuber, B.; Tschanz, S. A.; Zakrzewicz, A.; Egginton, S.; Berkholz, J. Structural Microangiopathies in Skeletal Muscle Related to Systemic Vascular Pathologies in Humans. Frontiers in physiology 2020, 11 (28), 28.

2019

Halbeisen, F. S.; Shoemark, A.; Barbato, A.; Boon, M.; Carr, S.; Crowley, S.; Hirst, R.; Karadag, B.; Koerner-Rettberg, C.; Loebinger, M. R.; Lucas, J. S.; Maitre, B.; Mazurek, H.; Özçelik, U.; Martinů, V.; Schwerk, N.; Thouvenin, G.; Tschanz, S. A.; Yiallouros, P.; Goutaki, M.; Kühni, C. Time Trends in Diagnostic Testing for PCD in Europe - Research Letter. European respiratory journal 2019, 54 (4), 1900528.

Goutaki, M.; Eich, M. O.; Halbeisen, F. S.; Barben, J.; Casaulta, C.; Clarenbach, C.; Hafen, G.; Latzin, P.; Regamey, N.; Lazor, R.; Tschanz, S. A.; Zanolari, M.; Maurer, E.; Kühni, C. The Swiss Primary Ciliary Dyskinesia Registry: Objectives, Methods and First Results. Swiss medical weekly 2019, 149, w20004.

2018

Beyeler, S. M.; Chortarea, S.; Rothen-Rutishauser, B.; Petri-Fink, A.; Wick, P.; Tschanz, S. A.; von Garnier, C.; Blank, F. Acute Effects of Multi-Walled Carbon Nanotubes on Primary Bronchial Epithelial Cells from COPD Patients. Nanotoxicology 2018, 12 (7), 699-711.

Mouton, W. G.; Wagner, M. O.; Haenni, B.; Mouton, K. T.; Ochs, M.; Tschanz, S. A. The Influence of Age on Valve Disease in Patients With Varicose Veins Analysed by Transmission Electron Microscopy and Stereology. Vasa - European journal of vascular medicine 2018, 47 (5), 409-416.

Hlushchuk, R.; Zubler, C. O.; Barré, S.; Correa Shokiche, C.; Schaad, L.; Röthlisberger, R.; Wnuk, M. L.; Daniel, C.; Khoma, O.-Z.; Tschanz, S. A.; Reyes Aguirre, M. A.; Djonov, V. G. Cutting-Edge Microangio-CT: New Dimensions in Vascular Imaging and Kidney Morphometry. American journal of physiology - renal physiology 2018, 314 (3), F493-F499.

Baum, O.; Sollberger, C.; Raaflaub, A.; Odriozola Quesada, A.; Spohr, G.; Frese, S.; Tschanz, S. A. Increased Capillary Tortuosity and Pericapillary Basement Membrane Thinning in Skeletal Muscle of Mice Undergoing Running Wheel Training. Journal of Experimental Biology 2018, 221 (Pt 4).

2017

Schögler, A.; Blank, F.; Brügger, M.; Beyeler, S. M.; Tschanz, S. A.; Regamey, N.; Casaulta, C.; Geiser, T.; Alves, M. Characterization of Pediatric Cystic Fibrosis Airway Epithelial Cell Cultures at the Air-Liquid Interface Obtained by Non-Invasive Nasal Cytology Brush Sampling. Respiratory research 2017, 18 (1), 215.

Baum, O.; Jentsch, L.; Odriozola Quesada, A.; Tschanz, S. A.; Olfert, I. M. Ultrastructure of Skeletal Muscles in Mice Lacking Muscle-Specific VEGF Expression. Anatomical record: advances in integrative anatomy and evolutionary biology 2017, 300 (12), 2239-2249.

Odriozola Quesada, A.; Llodra Gonzalez, J. A.; Radecke, J.; Ruegsegger, C.; Tschanz, S. A.; Saxena, S.; Rohr, S.; Zuber, B. High Contrast Staining for Serial Block Face Scanning Electron Microscopy Without Uranyl Acetate. Cold Spring Harbor Laboratory 2017.

2016

Bigler, M. R.; Koutsantonis, D.; Odriozola, A.; Halm, S.; Tschanz, S. A.; Zakrzewicz, A.; Weichert, A.; Baum, O. Morphometry of Skeletal Muscle Capillaries: The Relationship Between Capillary Ultrastructure and Ageing in Humans. Acta physiologica 2016, 218 (2), 98-111.

Beyeler, S. M.; Chortarea, S.; Rothen-Rutishauser, B.; Petri-Fink, A.; Wick, P.; Tschanz, S. A.; von Garnier, C.; Blank, F. Effects of Aerosolized Multi-Walled Carbon Nanotubes in Chronic Obstructive Pulmonary Disease: An Optimized Human in Vitro Airway Epithelial Model for Fibre Exposure at the Air-Liquid Interface, 2016.

Beyeler, S. M.; Chortarea, S.; Rothen-Rutishauser, B.; Petri-Fink, A.; Wick, P.; Tschanz, S. A.; von Garnier, C.; Blank, F. Effects of Aerosolized Multi-Walled Carbon Nanotubes in Chronic Obstructive Pulmonary Disease: An Optimized Human in Vitro Airway Epithelial Model for Fibre Exposure at the Air-Liquid Interface. BORIS Portal September 2016.

Beyeler, S. M.; Chortarea, S.; Rothen-Rutishauser, B.; Petri-Fink, A.; Tschanz, S. A.; von Garnier, C.; Blank, F. A Human in Vitro Airway Epithelial Model to Study the Effects of Aerosolized Multi-Walled Carbon Nanotubes in Chronic Obstructive Pulmonary Diseased Cells. BORIS Portal June 10, 2016.

Beyeler, S. M.; Chortarea, S.; Rothen-Rutishauser, B.; Petri-Fink, A.; Tschanz, S. A.; von Garnier, C.; Blank, F. A Human in Vitro Airway Epithelial Model to Study the Effects of Aerosolized Multi-Walled Carbon Nanotubes in Chronic Obstructive Pulmonary Diseased Cells, 2016.

Baum, O.; Torchetti, E.; Malik, C.; Hoier, B.; Walker, M.; Walker, P. J.; Odriozola Quesada, A.; Graber, F.; Tschanz, S. A.; Bangsbo, J.; Hoppeler, H.-H.; Askew, C. D.; Hellsten, Y. Capillary Ultrastructure and Mitochondrial Volume Density in Skeletal Muscle in Relation to Reduced Exercise Capacity of Patients With Intermittent Claudication. American journal of physiology - regulatory, integrative and comparative physiology 2016, 310 (10), R943-R951.

Hlushchuk, R.; Brönnimann, D.; Correa Shokiche, C.; Schaad, L.; Triet, R.; Jazwinska, A.; Tschanz, S. A.; Djonov, V. G. Zebrafish Caudal Fin Angiogenesis Assay-Advanced Quantitative Assessment Including 3-Way Correlative Microscopy. PLoS ONE 2016, 11 (3), e0149281.

2015

Baum, O.; Gübeli, J.; Frese, S.; Torchetti, E.; Malik, C.; Odriozola Quesada, A.; Graber, F.; Hoppeler, H.-H.; Tschanz, S. A. Angiogenesis-Related Ultrastructural Changes to Capillaries in Human Skeletal Muscle in Response to Endurance Exercise. Journal of applied physiology 2015, 119 (10), 1118-1126.

2014

Beyeler, S. M.; Chortarea, S.; Rothen-Rutishauser, B.; Petri-Fink, A.; Tschanz, S. A.; von Garnier, C.; Blank, F. Effects of Multi-Walled Carbon Nanotubes in Chronic Obstructive Pulmonary Disease: An Optimized Human in Vitro Airway Epithelial Model for Fibre Exposure at the Air-Liquid Interface, 2014.

Beyeler, S. M.; Chortarea, S.; Rothen-Rutishauser, B.; Petri-Fink, A.; Tschanz, S. A.; von Garnier, C.; Blank, F. Effects of Multi-Walled Carbon Nanotubes in Chronic Obstructive Pulmonary Disease: An Optimized Human in Vitro Airway Epithelial Model for Fibre Exposure at the Air-Liquid Interface, 2014.

Beyeler, S. M.; Chortarea, S.; Rothen-Rutishauser, B.; Petri-Fink, A.; Tschanz, S. A.; von Garnier, C.; Blank, F. A Human in Vitro Airway Epithelial Model to Study Health Effects of Multi-Walled Carbon Nanotubes (MWCNT). BORIS Portal November 5, 2014.

Beyeler, S. M.; Chortarea, S.; Rothen-Rutishauser, B.; Petri-Fink, A.; Tschanz, S. A.; von Garnier, C.; Blank, F. A Human in Vitro Airway Epithelial Model to Study Health Effects of Multi-Walled Carbon Nanotubes (MWCNT), 2014.

Tahedl, D.; Wirkes, A.; Tschanz, S. A.; Ochs, M.; Mühlfeld, C. How Common Is the Lipid Body-Containing Interstitial Cell in the Mammalian Lung?. American journal of physiology - lung cellular and molecular physiology 2014, 307 (5), L386-L394.

Tschanz, S. A.; Salm, L.; Roth-Kleiner, M.; Barré, S.; Burri, P. H.; Schittny, J. Rat Lungs Show a Biphasic Formation of New Alveoli During Postnatal Development. Journal of applied physiology 2014, 117 (1), 89-95.

Beyeler, S. M.; Chortarea, S.; Rothen-Rutishauser, B.; Petri-Fink, A.; Tschanz, S. A.; von Garnier, C.; Blank, F. A Human in Vitro Airway Wall Model to Study Effects of Multi-Walled Carbon Nanotubes on Cells from Healthy Subjects and Subjects Suffering from COPD. BORIS Portal May 9, 2014.

Beyeler, S. M.; Chortarea, S.; Rothen-Rutishauser, B.; Petri-Fink, A.; Tschanz, S. A.; von Garnier, C.; Blank, F. A Human in Vitro Airway Wall Model to Study Effects of Multi-Walled Carbon Nanotubes on Cells from Healthy Subjects and Subjects Suffering from COPD, 2014.

Roth-Kleiner, M.; Berger, T. M.; Gremlich, S.; Tschanz, S. A.; Mund, S.; Post, M.; Stampanoni, M.; Schittny, J. Neonatal Steroids Induce a down-Regulation of Tenascin-C and Elastin and Cause a Deceleration of the First Phase and an Acceleration of the Second Phase of Lung Alveolarization. Histochemistry and cell biology 2014, 141 (1), 75-84.

Tschanz, S. A.; Schneider, J. P.; Kundson, L. Design-Based Stereology: Planning, Volumetry and Sampling Are Crucial Steps for a Successful Study. Annals of anatomy - Anatomischer Anzeiger 2014, 196 (1), 3-11.

2013

Cremona, T. P.; Tschanz, S. A.; von Garnier, C.; Benarafa, C. SerpinB1 Deficiency Is Not Associated With Increased Susceptibility to Pulmonary Emphysema in Mice. American journal of physiology - lung cellular and molecular physiology 2013, 305 (12), L981-L989.

Haberthür, D.; Barré, S.; Tschanz, S. A.; Yao, E.; Stampanoni, M.; Schittny, J. Visualization and Stereological Characterization of Individual Rat Lung Acini by High-Resolution X-Ray Tomographic Microscopy. Journal of applied physiology 2013, 115 (9), 1379-1387.

Mouton, W. G.; Habegger, A. K.; Haenni, B.; Tschanz, S. A.; Baumgartner, I.; Ochs, M. Valve Disease in Chronic Venous Disorders: A Quantitative Ultrastructural Analysis by Transmission Electron Microscopy and Stereology. Swiss medical weekly 2013, 143 (w13755), w13755.

Schätz, G.; Schneiter, M. M.; Ricka, J.; Kühni, K.; Tschanz, S. A.; Doherr, M.; Frenz, M.; Stoffel, M. H. Ciliary Beating Plane and Wave Propagation in the Bovine Oviduct. Cells tissues organs 2013, 198 (6), 457-469.

2012

Riche, F.; Schneebeli, M.; Tschanz, S. A. Design-Based Stereology to Quantify Structural Properties of Artificial and Natural Snow Using Thin Sections. Cold regions science and technology 2012, 2012 (79-80), 67-74.

2011

Lélu, K.; Laffont, S.; Delpy, L.; Paulet, P.-E.; Périnat, T.; Tschanz, S. A.; Pelletier, L.; Engelhardt, B.; Guéry, J.-C. Estrogen Receptor α Signaling in T Lymphocytes Is Required for Estradiol-Mediated Inhibition of Th1 and Th17 Cell Differentiation and Protection Against Experimental Autoimmune Encephalomyelitis. Journal of immunology 2011, 187 (5), 2386-93.

Tschanz, S. A.; Burri, P. H.; Weibel, E. R. A Simple Tool for Stereological Assessment of Digital Images: The STEPanizer. Journal of microscopy 2011, 243 (1), 47-59.

2010

Baum, O.; Suter, F.; Gerber, B.; Tschanz, S. A.; Buergy, R.; Blank, F.; Hlushchuk, R.; Djonov, V. G. VEGF-A Promotes Intussusceptive Angiogenesis in the Developing Chicken Chorioallantoic Membrane. Microcirculation 2010, 17 (6), 447-57.

2007

Tschanz, S. A. Structural Aspects of Pre-and Post-Natal Lung Development. Pneumologie 2007, 61 (7), 479-481.

Makanya, A. N.; Tschanz, S. A.; Haenni, B.; Burri, P. H. Functional Respiratory Morphology in the Newborn Quokka Wallaby (Setonix Brachyurus). Journal of anatomy 2007, 211 (1), 26-36.

Tschanz, S. A.; Burri, P. H. Morphologie Der Lunge Und Entwicklung Des Gasaustauschapparates. In Pädiatrie (3rd ed.); Lentze, M. J., Schulte, F. J., Schaub, J., Spranger, J., Eds.; Springer Medizin Verlag: Heidelberg, 2007; pp. 990-995.

2004

Ehrbar, M.; Djonov, V. G.; Schnell, C.; Tschanz, S. A.; Martiny-Baron, G.; Schenk, U.; Wood, J.; Burri, P. H.; Hubbell, J. A.; Zisch, A. H. Cell-Demanded Liberation of VEGF121 from Fibrin Implants Induces Local and Controlled Blood Vessel Growth. Circulation research 2004, 94 (8), 1124-1132.

Tschanz, S. A.; Burri, P. H. Prä- Und Postnatale Entwicklung Und Wachstum Der Lunge. In Pädiatrische Pneumologie; Rieger, C., Hardt, H. von der, Sennhauser, F. H., Wahn, U., Zach, M., Eds.; Springer: Berlin, 2004; pp. 3-15.

Frey, G.; Egli, E.; Chailley-Heu, B.; Lelièvre-Pégorier, M.; Burri, P. H.; Bourbon, J.; Tschanz, S. A. Effects of Mild Vitamin a Deficiency on Lung Maturation in Newborn Rats: A Morphometric and Morphologic Study. Biology of the Neonate 2004, 86 (4), 259-268.

2003

Burri, P. H.; Haenni, B.; Tschanz, S. A.; Makanya, A. N. Morphometry and Allometry of the Postnatal Marsupial Lung Development: An Ultrastructural Study. Respiratory physiology & neurobiology 2003, 138 (2-3), 309-324.

Schwyter, M.; Burri, P. H.; Tschanz, S. A. Geometric Properties of the Lung Parenchyma After Postnatal Glucocorticoid Treatment in Rats. Biology of the Neonate 2003, 83 (1), 57-64.

Tschanz, S. A.; Makanya, A. N.; Haenni, B.; Burri, P. H. Effects of Neonatal High-Dose Short-Term Glucocorticoid Treatment on the Lung: A Morphologic and Morphometric Study in the Rat. Pediatric research 2003, 53 (1), 72-80.

2002

Meier, F. M.; Tschanz, S. A.; Ganzfried, R.; Epstein, D. A Comparative Assessment of Endothelium from Pseudophakic and Phakic Donor Corneas Stored in Organ Culture. British journal of ophthalmology 2002, 86 (4), 400-403.

Tschanz, S. A.; Burri, P. H. A New Approach to Detect Structural Differences in Lung Parenchyma Using Digital Image Analysis. Experimental lung research 2002, 28 (6), 457-471.

2001

Ellis, T.; Gambardella, L.; Horcher, M.; Tschanz, S. A.; Capol, J.; Bertram, P.; Jochum, W.; Barrandon, Y.; Busslinger, M. The Transcriptional Repressor CDP (Cutl1) Is Essential for Epithelial Cell Differentiation of the Lung and the Hair Follicle. Genes & development 2001, 15 (17), 2307-2319.

2000

Tschanz, S. A.; Haenni, B.; Burri, P. H. Glucocorticoid Induced Impairment of Lung Structure Assessed by Digital Image Analysis. European journal of pediatrics 2000, 161 (1), 26-30.

Djonov, V. G.; Schmid, M.; Tschanz, S. A.; Burri, P. H. Intussusceptive Angiogenesis: Its Role in Embryonic Vascular Network Formation. Circulation research 2000, 86 (3), 286-292.

1999

Duebener, L. F.; Takahashi, Y.; Wada, H.; Tschanz, S. A.; Burri, P. H.; Schäfers, H.-J. Do Mature Pulmonary Lobes Grow After Transplantation into an Immature Recipient?. The Annals of Thoracic Surgery 1999, 68 (4), 1165-1170.

1997

Makanya, A. N.; Maina, J. N.; Mayhew, T. M.; Tschanz, S. A.; Burri, P. H. A Stereological Comparison of Villous and Microvillous Surfaces in Small Intestines of Frugivorous and Entomophagous Bats: Species, Inter-Individual and Craniocaudal Differences. Journal of Experimental Biology 1997, 200 (Pt 18), 2415-2423.

Tschanz, S. A.; Burri, P. H. Postnatal Lung Development and Its Impairment by Glucocorticoids. Pediatric pulmonology 1997, 16, 247-249.

1995

Kalenga, M.; Tschanz, S. A.; Burri, P. H. Protein Deficiency and the Growing Rat Lung. I. Nutritional Findings and Related Lung Volumes. Pediatric research 1995, 37 (6), 783-788.

Tschanz, S. A.; Damke, B. M.; Burri, P. H. Influence of Postnatally Administered Glucocorticoids on Rat Lung Growth. Biology of the Neonate 1995, 68 (4), 229-245.

Kalenga, M.; Tschanz, S. A.; Burri, P. H. Protein Deficiency and the Growing Rat Lung. II. Morphometric Analysis and Morphology. Pediatric research 1995, 37 (6), 789-795.