2025
Besançon, H.; Polidori, M.; Hostettler, A.; Nizet, V.; Oevermann, A.; Babiychuk, E. Liposomal Nanotraps Neutralize Listeria Monocytogenes Toxins to Enhance Macrophage Viability and Antibacterial Capacity. Infectious Microbes & Diseases 2025.
2023
Müller, A. K.; Lekhuleni, C.; Hupp, S.; du Plessis, M.; Holivololona, L.; Babiichuk, E.; Leib, S.; Grandgirard, D.; Iliev, A. I.; von Gottberg, A.; Hathaway, L. J. Meningitis-Associated Pneumococcal Serotype 8, ST 53, Strain Is Hypervirulent in a Rat Model and Has Non-Haemolytic Pneumolysin Which Can Be Attenuated by Liposomes. Frontiers in cellular and infection microbiology 2023, 12.
2022
Wolfmeier, H.; Wardell, S. J. T.; Liu, L. T.; Falsafi, R.; Draeger, A.; Babiichuk, E.; Pletzer, D.; Hancock, R. E. W. Targeting the Pseudomonas Aeruginosa Virulence Factor Phospholipase C With Engineered Liposomes. Frontiers in Microbiology 2022, 13, 867449.
Besançon, H.; Larpin, Y.-N.; Babiychuk, V.; Köffel, R.; Babiichuk, E. Engineered Liposomes Protect Immortalized Immune Cells from Cytolysins Secreted by Group A and Group G Streptococci. Cells 2022, 11 (1).
2021
Besançon, H.; Babiichuk, V.; Larpin, Y.-N.; Köffel, R.; Schittny, D. C.; Brockhus, L. A.; Hathaway, L. J.; Sendi, P.; Draeger, A.; Babiichuk, E. Tailored Liposomal Nanotraps for the Treatment of Streptococcal Infections. Journal of nanobiotechnology 2021, 19 (1), 46.
2020
Larpin, Y.-N.; Besançon, H.; Iacovache, M. I.; Babiichuk, V.; Babiichuk, E.; Zuber, B.; Draeger, A.; Köffel, R. Bacterial Pore-Forming Toxin Pneumolysin: Cell Membrane Structure and Microvesicle Shedding Capacity Determines Differential Survival of Immune Cell Types. FASEB journal 2020, 34 (1), 1665-1678.
Lang, J.; Bohn, P.; Bhat, H.; Jastrow, H.; Walkenfort, B.; Cansiz, F.; Fink, J.; Bauer, M.; Olszewski, D.; Ramos-Nascimento, A.; Duhan, V.; Friedrich, S.-K.; Becker, K. A.; Krawczyk, A.; Edwards, M. J.; Burchert, A.; Huber, M.; Friebus-Kardash, J.; Göthert, J. R.; Hardt, C.; Probst, H. C.; Schumacher, F.; Köhrer, K.; Kleuser, B.; Babiichuk, E.; Sodeik, B.; Seibel, J.; Greber, U. F.; Lang, P. A.; Gulbins, E.; Lang, K. S. Acid Ceramidase of Macrophages Traps Herpes Simplex Virus in Multivesicular Bodies and Protects from Severe Disease. Nature Communications 2020, 11 (1), 1338.
2019
Schönauer, R.; Larpin, Y.-N.; Babiichuk, E.; Drücker, P.; Babiichuk, V.; Avota, E.; Schneider-Schaulies, S.; Schumacher, F.; Kleusner, B.; Köffel, R.; Draeger, A. Down-Regulation of Acid Sphingomyelinase and Neutral Sphingomyelinase-2 Inversely Determines the Cellular Resistance to Plasmalemmal Injury by Pore-Forming Toxins. FASEB journal 2019, 33 (1), 275-285.
Drücker, P.; Iacovache, M. I.; Bachler, S.; Zuber, B.; Babiichuk, E.; Dittrich, P. S.; Draeger, A. Membrane Deformation and Layer-by-Layer Peeling of Giant Vesicles Induced by the Pore-Forming Toxin Pneumolysin. Biomaterials science 2019, 7 (9), 3693-3705.
2018
Drücker, P.; Bachler, S.; Wolfmeier, H. A.; Schönauer, R.; Köffel, R.; Babiychuk, V. S.; Dittrich, P. S.; Draeger, A.; Babiichuk, E. Pneumolysin-Damaged Cells Benefit from Non-Homogeneous Toxin Binding to Cholesterol-Rich Membrane Domains. Biochimica and biophysica acta - molecular and cell biology of lipids 2018, 1863 (8), 795-805.
Köffel, R.; Wolfmeier, H. A.; Larpin, Y.-N.; Besançon, H.; Schönauer, R.; Babiichuk, V.; Drücker, P.; Pabst, T. N.; Mitchell, T.; Babiichuk, E.; Draeger, A. Host-Derived Microvesicles Carrying Bacterial Pore-Forming Toxins Deliver Signals to Macrophages: A Novel Mechanism of Shaping Immune Responses. Frontiers in immunology 2018, 9 (1688), 1688.
Wolfmeier, H. A.; Mansour, S. C.; Liu, L. T.; Pletzer, D.; Draeger, A.; Babiichuk, E.; Hancock, R. E. W. Liposomal Therapy Attenuates Dermonecrosis Induced by Community-Associated Methicillin-Resistant Staphylococcus Aureus by Targeting α-Type Phenol-Soluble Modulins and α-Hemolysin. EBioMedicine 2018, 33, 211-217.
2016
Wolfmeier, H. A.; Radecke, J.; Schönauer, R.; Köffel, R.; Babiichuk, V.; Drücker, P.; Hathaway, L. J.; Mitchell, T. J.; Zuber, B.; Draeger, A.; Babiichuk, E. Active Release of Pneumolysin Prepores and Pores by Mammalian Cells Undergoing a Streptococcus Pneumoniae Attack. Biochimica et biophysica acta (BBA) - general subjects 2016, 1860 (11 Pt A), 2498-2509.
Baumgartner, D.; Aebi, S.; Grandgirard, D.; Leib, S.; Draeger, A.; Babiichuk, E.; Hathaway, L. J. Clinical Streptococcus Pneumoniae Isolates Induce Differing CXCL8 Responses from Human Nasopharyngeal Epithelial Cells Which Are Reduced by Liposomes. BMC microbiology 2016, 16 (1), 154.
2015
Babiichuk, E.; Draeger, A. Defying Death: Cellular Survival Strategies Following Plasmalemmal Injury by Bacterial Toxins. Seminars in cell & developmental biology 2015, 45, 39-47.
Draeger, A.; Schönauer, R.; Babiichuk, E.; Atanassoff, A. P.; Wolfmeier, H. A. Ca2+-Dependent Repair of Pneumolysin Pores: A New Paradigm for Host Cellular Defense Against Bacterial Pore-Forming Toxins. Biochimica et biophysica acta - molecular cell research 2015, 1853 (9), 2045-2054.
2014
Draeger, A.; Babiichuk, E.; Schönauer, R.; Atanassoff, A. P.; Wolfmeier, H. A. Dealing With Damage: Plasma Membrane Repair Mechanisms. Biochimie 2014, 107 (Part A), 66-72.
Schönauer, R.; Atanassoff, A. P.; Wolfmeier, H. A.; Pelegrin, P.; Babiichuk, E.; Draeger, A. P2X7 Receptors Mediate Resistance to Toxin-Induced Cell Lysis. Biochimica et biophysica acta - molecular cell research 2014, 1843 (5), 915-922.
Atanassoff, A. P.; Wolfmeier, H. A.; Schönauer, R.; Hostettler, A.; Ring, A.; Draeger, A.; Babiichuk, E. Microvesicle Shedding and Lysosomal Repair Fulfill Divergent Cellular Needs During the Repair of Streptolysin O-Induced Plasmalemmal Damage. PLoS ONE 2014, 9 (2), e89743.
Babiichuk, E.; Draeger, A.; Wolfmeier, H. A.; Luginbühl, M. Engineered Liposomes Sequester Bacterial Exotoxins and Protect from Severe Invasive Infections in Mice. Nature biotechnology 2014, 33 (1), 81-88.
2013
Monastyrskaya-Stäuber, K.; Babiichuk, E.; Draeger, A.; Burkhard, F. C. Down-Regulation of Annexin A1 in the Urothelium Decreases Cell Survival After Bacterial Toxin Exposure. Journal of urology 2013, 190 (1), 325-333.
Voigt, T.; Sebald, H.-J.; Schönauer, R.; Levano, S.; Girard, T.; Hoppeler, H.-H.; Babiichuk, E.; Draeger, A. Annexin A1 Is a Biomarker of T-Tubular Repair in Skeletal Muscle of Nonmyopathic Patients Undergoing Statin Therapy. FASEB journal 2013, 27 (6), 2156-2164.
Draeger, A.; Babiichuk, E. Ceramide in Plasma Membrane Repair. In Sphingolipids in Disease; Gulbins, E., Petrache, I., Eds.; Handbook of Experimental Pharmacology; Springer: Vienna, 2013; Vol. 216, pp. 341-353.
2012
Draeger, A.; Babiichuk, E. Annexins. In Encyclopedia of Mettalloproteins; Kretsinger RH, U. V., Ed.; Springer London Ltd.: London, 2012.
Draeger, A.; Babiichuk, E. Annexins. Encyclopedia of Metalloproteins; Kretsinger, R. H., Uversky, V. N., Permyakov, E. A., Eds.; Springer: New York, 2012; pp. 68-73.
2011
Draeger, A.; Monastyrskaya-Stäuber, K.; Babiichuk, E. Plasma Membrane Repair and Cellular Damage Control: The Annexin Survival Kit. Biochemical pharmacology 2011, 81 (6), 703-12.
Babiichuk, E.; Atanassoff, A. P.; Monastyrskaya, K.; Brandenberger, C.; Studer, D. F.; Allemann, C.; Draeger, A. The Targeting of Plasmalemmal Ceramide to Mitochondria During Apoptosis. PLoS ONE 2011, 6 (8), e23706.
Potez, S.; Luginbühl, M.; Monastyrskaya, K.; Hostettler, A.; Draeger, A.; Babiichuk, E. Tailored Protection Against Plasmalemmal Injury by Annexins With Different Ca2+ Sensitivities. Journal of biological chemistry 2011, 286 (20), 17982-91.
Babiichuk, E.; Monastyrskaya-Stäuber, K.; Potez, S.; Draeger, A. Blebbing Confers Resistance Against Cell Lysis. Cell death and differentiation 2011, 18 (1), 80-9.
2010
Draeger, A.; Sanchez Freire, V.; Monastyrskaya-Stäuber, K.; Hoppeler, H.-H.; Mueller, M.; Breil, F.; Mohaupt, M.; Babiichuk, E. Statin Therapy and the Expression of Genes That Regulate Calcium Homeostasis and Membrane Repair in Skeletal Muscle. American journal of pathology 2010, 177 (1), 291-9.
2009
Monastyrskaya, K.; Babiichuk, E.; Hostettler, A.; Wood, P.; Grewal, T.; Draeger, A. Plasma Membrane-Associated Annexin A6 Reduces Ca2+ Entry by Stabilizing the Cortical Actin Cytoskeleton. Journal of biological chemistry 2009, 284 (25), 17227-42.
Monastyrskaya, K.; Babiichuk, E.; Draeger, A. The Annexins: Spatial and Temporal Coordination of Signaling Events During Cellular Stress. Cellular and molecular life sciences 2009, 66 (16), 2623-42.
Mohaupt, M.; Karas, R.; Babiichuk, E.; Sanchez Freire, V.; Monastyrskaya-Stäuber, K.; Iyer, L.; Hoppeler, H.-H.; Breil, F.; Draeger, A. Association Between Statin-Associated Myopathy and Skeletal Muscle Damage. CMAJ 2009, 181 (1-2), E11-8.
Babiichuk, E.; Monastyrskaya, K.; Potez, S.; Draeger, A. Intracellular Ca(2+) Operates a Switch Between Repair and Lysis of Streptolysin O-Perforated Cells. Cell death and differentiation 2009, 16 (8), 1126-34.
2008
Babiichuk, E.; Monastyrskaya, K.; Draeger, A. Fluorescent Annexin A1 Reveals Dynamics of Ceramide Platforms in Living Cells. Traffic 2008, 9 (10), 1757-75.
Monastyrskaya, K.; Tschumi, F.; Babiichuk, E.; Keogh-Stroka, D. M.; Draeger, A. Annexins Sense Changes in Intracellular PH During Hypoxia. Biochemical journal 2008, 409 (1), 65-75.
2007
De Schutter, K.; Joubès, J.; Cools, T.; Verkest, A.; Corellou, F.; Babiichuk, E.; Van Der Schueren, E.; Beeckman, T.; Kushnir, S.; Inzé, D.; De Veylder, L. Arabidopsis WEE1 Kinase Controls Cell Cycle Arrest in Response to Activation of the DNA Integrity Checkpoint. The Plant Cell 2007, 19 (1), 211-25.
Monastyrskaya-Stäuber, K.; Babiichuk, E.; Hostettler, A.; Rescher, U.; Draeger, A. Annexins As Intracellular Calcium Sensors. Cell calcium 2007, 41 (3), 207-19.
2006
Babiichuk, E.; Draeger, A. Regulation of Ecto-5’-Nucleotidase Activity via Ca2+-Dependent, Annexin 2-Mediated Membrane Rearrangement?. Biochemical Society transactions 2006, 34 (Pt 3), 374-6.
Babiichuk, E.; Draeger, A. Biochemical Characterization of Detergent-Resistant Membranes: A Systematic Approach. Biochemical journal 2006, 397 (3), 407-16.
Draeger, A.; Monastyrskaya-Stäuber, K.; Mohaupt, M.; Hoppeler, H.-H.; Savolainen, H. O.; Allemann, C.; Babiichuk, E. Statin Therapy Induces Ultrastructural Damage in Skeletal Muscle in Patients Without Myalgia. Journal of pathology 2006, 210 (1), 94-102.
Matschke, K.; Babiichuk, E.; Monastyrskaya-Stäuber, K.; Draeger, A. Phenotypic Conversion Leads to Structural and Functional Changes of Smooth Muscle Sarcolemma. Experimental cell research 2006, 312 (18), 3495-503.
2004
Babiichuk, E.; Smith, R. D.; Burdyga, T.; Babiychuk, V. S.; Wray, S.; Draeger, A. Membrane Cholesterol Regulates Smooth Muscle Phasic Contraction. The Journal of Membrane Biology 2004, 198 (2), 95-101.
2003
Monastyrskaya-Stäuber, K.; Babiichuk, E.; Schittny, J.; Rescher, U.; Gerke, V.; Mannherz, H.-G.; Draeger, A. The Expression Levels of Three Raft-Associated Molecules in Cultivated Vascular Cells Are Dependent on Culture Conditions. Cellular and molecular life sciences 2003, 60 (12), 2702-2709.
