2022
Wolfmeier, Heidi; Wardell, Samuel J T; Liu, Leo T; Falsafi, Reza; Draeger, Annette; Babiychuk, Eduard B; Pletzer, Daniel; Hancock, Robert E W (2022). Targeting the Pseudomonas aeruginosa Virulence Factor Phospholipase C With Engineered Liposomes. Frontiers in Microbiology, 13, pp. 867449. Frontiers 10.3389/fmicb.2022.867449
2021
Besançon, Hervé; Babiychuk, Viktoriia; Larpin, Yu; Köffel, René; Schittny, Dominik; Brockhus, Lara; Hathaway, Lucy J.; Sendi, Parham; Draeger, Annette; Babiichuk, Eduard (2021). Tailored liposomal nanotraps for the treatment of Streptococcal infections. Journal of nanobiotechnology, 19(1), pp. 46. BioMed Central 10.1186/s12951-021-00775-x
2020
Larpin, Yu; Besançon, Hervé; Iacovache, Mircea Ioan; Babiychuk, Victoriia S.; Babiychuk, Eduard B.; Zuber, Benoît; Draeger, Annette; Köffel, René (2020). Bacterial pore-forming toxin pneumolysin: Cell membrane structure and microvesicle shedding capacity determines differential survival of immune cell types. FASEB journal, 34(1), pp. 1665-1678. Federation of American Societies for Experimental Biology 10.1096/fj.201901737RR
2019
Schönauer, Roman; Larpin, Yu-Noël; Babiychuk, Eduard; Drücker, Patrick; Babiychuk, Victoria; Avota, E; Schneider-Schaulies, S; Schumacher, F; Kleusner, B; Köffel, René; Draeger, Annette (2019). Down-regulation of acid sphingomyelinase and neutral sphingomyelinase-2 inversely determines the cellular resistance to plasmalemmal injury by pore-forming toxins. FASEB journal, 33(1), pp. 275-285. Federation of American Societies for Experimental Biology 10.1096/fj.201800033R
Drücker, Patrick; Iacovache, Ioan; Bachler, Simon; Zuber, Benoît; Babiychuk, Eduard B.; Dittrich, Petra S.; Draeger, Annette (2019). Membrane deformation and layer-by-layer peeling of giant vesicles induced by the pore-forming toxin pneumolysin. Biomaterials science, 7(9), pp. 3693-3705. Royal Society of Chemistry 10.1039/C9BM00134D
2018
Drücker, Patrick; Bachler, Simon; Wolfmeier, Heidi Annemarie; Schönauer, Roman; Köffel, René; Babiychuk, Viktoria S; Dittrich, Petra S; Draeger, Annette; Babiychuk, Eduard (2018). Pneumolysin-damaged cells benefit from non-homogeneous toxin binding to cholesterol-rich membrane domains. Biochimica and biophysica acta - molecular and cell biology of lipids, 1863(8), pp. 795-805. Elsevier 10.1016/j.bbalip.2018.04.010
Köffel, René; Wolfmeier, Heidi Annemarie; Larpin, Yu Noël; Besançon, Hervé; Schönauer, Roman; Babiychuk, Victoria; Drücker, Patrick; Pabst, Thomas; Mitchell, TJ; Babiychuk, Eduard; Draeger, Annette (2018). Host-Derived Microvesicles Carrying Bacterial Pore-Forming Toxins Deliver Signals to Macrophages: A Novel Mechanism of Shaping Immune Responses. Frontiers in immunology, 9(1688), pp. 1688. Frontiers Research Foundation 10.3389/fimmu.2018.01688
Wolfmeier, Heidi Annemarie; Mansour, Sarah C; Liu, Leo T; Pletzer, Daniel; Draeger, Annette; Babiychuk, Eduard; Hancock, Robert E W (2018). Liposomal Therapy Attenuates Dermonecrosis Induced by Community-Associated Methicillin-Resistant Staphylococcus aureus by Targeting α-Type Phenol-Soluble Modulins and α-Hemolysin. EBioMedicine, 33, pp. 211-217. Elsevier 10.1016/j.ebiom.2018.06.016
2016
Wolfmeier, Heidi Annemarie; Radecke, Julika; Schönauer, Roman; Köffel, René; Babiychuk, Victoria; Drücker, Patrick; Hathaway, Lucy Jane; Mitchell, Timothy J; Zuber, Benoît; Draeger, Annette; Babiychuk, Eduard (2016). Active release of pneumolysin prepores and pores by mammalian cells undergoing a Streptococcus pneumoniae attack. Biochimica et biophysica acta (BBA) - general subjects, 1860(11 Pt A), pp. 2498-2509. Elsevier 10.1016/j.bbagen.2016.07.022
Baumgartner, Denja; Aebi, Susanne; Grandgirard, Denis; Leib, Stephen; Draeger, Annette; Babiychuk, Eduard; Hathaway, Lucy Jane (2016). Clinical Streptococcus pneumoniae isolates induce differing CXCL8 responses from human nasopharyngeal epithelial cells which are reduced by liposomes. BMC microbiology, 16(1), pp. 154. BioMed Central 10.1186/s12866-016-0777-5
2015
Babiychuk, Eduard; Draeger, Annette (2015). Defying death: Cellular survival strategies following plasmalemmal injury by bacterial toxins. Seminars in cell & developmental biology, 45, pp. 39-47. Elsevier 10.1016/j.semcdb.2015.10.016
Draeger, Annette; Schönauer, Roman; Babiychuk, Eduard; Atanassoff, Alexander P.; Wolfmeier, Heidi Annemarie (2015). Ca2+-dependent repair of pneumolysin pores: A new paradigm for host cellular defense against bacterial pore-forming toxins. Biochimica et biophysica acta - molecular cell research, 1853(9), pp. 2045-2054. Elsevier 10.1016/j.bbamcr.2014.09.005
2014
Draeger, Annette; Babiychuk, Eduard; Schönauer, Roman; Atanassoff, Alexander P.; Wolfmeier, Heidi Annemarie (2014). Dealing with damage: Plasma membrane repair mechanisms. Biochimie, 107(Part A), pp. 66-72. Elsevier Masson SAS 10.1016/j.biochi.2014.08.008
Schönauer, Roman; Atanassoff, Alexander P.; Wolfmeier, Heidi Annemarie; Pelegrin, Pablo; Babiychuk, Eduard; Draeger, Annette (2014). P2X7 receptors mediate resistance to toxin-induced cell lysis. Biochimica et biophysica acta - molecular cell research, 1843(5), pp. 915-922. Elsevier 10.1016/j.bbamcr.2014.01.024
Atanassoff, Alexander P.; Wolfmeier, Heidi; Schoenauer, Roman; Hostettler, Andrea; Ring, Avi; Draeger, Annette; Babiychuk, Eduard B. (2014). Microvesicle Shedding and Lysosomal Repair Fulfill Divergent Cellular Needs during the Repair of Streptolysin O-Induced Plasmalemmal Damage. PLoS ONE, 9(2), pp. e89743. Public Library of Science 10.1371/journal.pone.0089743
Babiychuk, Eduard; Draeger, Annette; Wolfmeier, Heidi Annemarie; Luginbühl, Miriam (2014). Engineered liposomes sequester bacterial exotoxins and protect from severe invasive infections in mice. Nature biotechnology, 33(1), pp. 81-88. Nature America 10.1038/nbt.3037
2013
Monastyrskaya, Katia; Babiychuk, Eduard B.; Draeger, Annette; Burkhard, Fiona C. (2013). Down-Regulation of Annexin A1 in the Urothelium Decreases Cell Survival After Bacterial Toxin Exposure. Journal of urology, 190(1), pp. 325-333. Elsevier 10.1016/j.juro.2013.01.088
Voigt, Tilman; Sebald, Hans-Jörg; Schoenauer, Roman; Levano, Soledad; Girard, Thierry; Hoppeler, Hans H.; Babiychuk, Eduard B.; Draeger, Annette (2013). Annexin A1 is a biomarker of T-tubular repair in skeletal muscle of nonmyopathic patients undergoing statin therapy. FASEB journal, 27(6), pp. 2156-2164. Federation of American Societies for Experimental Biology 10.1096/fj.12-219345
Draeger, Annette; Babiychuk, Eduard B.; Gulbins, Erich; Petrache, Irina (2013). Ceramide in Plasma Membrane Repair. 216, pp. 341-353. Springer 10.1007/978-3-7091-1511-4_17
Monastyrskaya, Katia; Sánchez-Freire, Verónica; Hashemi Gheinani, Ali; Klumpp, David J; Babiychuk, Eduard B; Draeger, Annette; Burkhard, Fiona C (2013). miR-199a-5p regulates urothelial permeability and may play a role in bladder pain syndrome. American journal of pathology, 182(2), pp. 431-48. Elsevier 10.1016/j.ajpath.2012.10.020
2012
Draeger, Annette; Babiychuk, Eduard; Kretsinger, Robert H; Uversky, Vladimir N; Permyakov, Eugene A (2012). Annexins. , pp. 68-73. Springer 10.1007/978-1-4614-1533-6_59
Draeger, A; Babiychuk, E; Kretsinger RH, Uversky VN (2012). Annexins. Springer London Ltd.
2011
Babiychuk, EB; Draeger, A (2011). Die Reparatur der Zellmembran: die Werkstatt der Annexine. GIT - Labor-Fachzeitschrift, (8), pp. 550-551. GIT-Verlag
Babiychuk, Eduard B.; Atanassoff, Alexander P.; Monastyrskaya, Katia; Brandenberger, Christina; Studer, Daniel; Allemann, Catherine; Draeger, Annette (2011). The targeting of plasmalemmal ceramide to mitochondria during apoptosis. PLoS ONE, 6(8), pp. e23706. Public Library of Science 10.1371/journal.pone.0023706
Babiychuk, E B; Monastyrskaya, K; Potez, S; Draeger, A (2011). Blebbing confers resistance against cell lysis. Cell death and differentiation, 18(1), pp. 80-9. Nature Publishing Group 10.1038/cdd.2010.81
Draeger, Annette; Monastyrskaya-Stäuber, Katia; Babiychuk, Eduard B (2011). Plasma membrane repair and cellular damage control: the annexin survival kit. Biochemical pharmacology, 81(6), pp. 703-12. Elsevier 10.1016/j.bcp.2010.12.027
Potez, Sarah; Luginbühl, Miriam; Monastyrskaya, Katia; Hostettler, Andrea; Draeger, Annette; Babiychuk, Eduard B (2011). Tailored protection against plasmalemmal injury by annexins with different Ca2+ sensitivities. Journal of biological chemistry, 286(20), pp. 17982-91. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M110.187625
2010
Draeger, Annette; Sanchez-Freire, Verónica; Monastyrskaya, Katia; Hoppeler, Hans; Mueller, Matthias; Breil, Fabio; Mohaupt, Markus G; Babiychuk, Eduard B (2010). Statin therapy and the expression of genes that regulate calcium homeostasis and membrane repair in skeletal muscle. American journal of pathology, 177(1), pp. 291-9. Elsevier 10.2353/ajpath.2010.091140
Draeger, A; Sanchez-Freire, V; Babiychuk, EB; Monastyrskaya, K; Hoppeler, H; Mohaupt, MG (2010). Statine-gut fürs Herz, problematisch für die Muskeln. Schweizerisches Medizin-Forum SMF / Swiss medical forum / Forum médical suisse FMS, EMH Editores Medicorum Helveticorum
2009
Babiychuk, E B; Monastyrskaya, K; Potez, S; Draeger, A (2009). Intracellular Ca(2+) operates a switch between repair and lysis of streptolysin O-perforated cells. Cell death and differentiation, 16(8), pp. 1126-34. Nature Publishing Group 10.1038/cdd.2009.30
Mohaupt, MG; Karas, RH; Babiychuk, EB; Sanchez-Freire, V; Monastyrskaya, K; Iyer, L; Hoppeler, H; Breil, F; Draeger, A (2009). Association between statin-associated myopathy and skeletal muscle damage. CMAJ, 181(1-2), pp. E11-8. Canadian Medical Association 10.1503/cmaj.081785
Monastyrskaya, Katia; Babiychuk, Eduard B; Draeger, Annette (2009). The annexins: spatial and temporal coordination of signaling events during cellular stress. Cellular and molecular life sciences, 66(16), pp. 2623-42. SP Birkhäuser Verlag Basel 10.1007/s00018-009-0027-1
Monastyrskaya, Katia; Babiychuk, Eduard B; Hostettler, Andrea; Wood, Peta; Grewal, Thomas; Draeger, Annette (2009). Plasma membrane-associated annexin A6 reduces Ca2+ entry by stabilizing the cortical actin cytoskeleton. Journal of biological chemistry, 284(25), pp. 17227-42. American Society for Biochemistry and Molecular Biology 10.1074/jbc.M109.004457
2008
Babiychuk, Eduard B; Monastyrskaya, Katia; Draeger, Annette (2008). Fluorescent annexin A1 reveals dynamics of ceramide platforms in living cells. Traffic, 9(10), pp. 1757-75. Wiley-Blackwell 10.1111/j.1600-0854.2008.00800.x
Monastyrskaya, Katia; Tschumi, Fabian; Babiychuk, Eduard B; Stroka, Deborah; Draeger, Annette (2008). Annexins sense changes in intracellular pH during hypoxia. Biochemical journal, 409(1), pp. 65-75. Portland Press 10.1042/BJ20071116
2007
Monastyrskaya, Katia; Babiychuk, Eduard B; Hostettler, Andrea; Rescher, Ursula; Draeger, Annette (2007). Annexins as intracellular calcium sensors. Cell calcium, 41(3), pp. 207-19. Elsevier 10.1016/j.ceca.2006.06.008
2006
Babiychuk, E B; Draeger, A (2006). Regulation of ecto-5'-nucleotidase activity via Ca2+-dependent, annexin 2-mediated membrane rearrangement?. Biochemical Society transactions, 34(Pt 3), pp. 374-6. Portland Press
Babiychuk, Eduard B; Draeger, Annette (2006). Biochemical characterization of detergent-resistant membranes: a systematic approach. Biochemical journal, 397(3), pp. 407-16. Portland Press 10.1042/BJ20060056
Draeger, A; Monastyrskaya, K; Mohaupt, M; Hoppeler, H; Savolainen, H; Allemann, C; Babiychuk, E B (2006). Statin therapy induces ultrastructural damage in skeletal muscle in patients without myalgia. Journal of pathology, 210(1), pp. 94-102. Wiley 10.1002/path.2018
Matschke, Katharina; Babiychuk, Eduard B; Monastyrskaya, Katia; Draeger, Annette (2006). Phenotypic conversion leads to structural and functional changes of smooth muscle sarcolemma. Experimental cell research, 312(18), pp. 3495-503. Elsevier 10.1016/j.yexcr.2006.07.012
2004
Babiychuk, E. B.; Smith, R. D.; Burdyga, T.; Babiychuk, V. S.; Wray, S.; Draeger, A. (2004). Membrane Cholesterol Regulates Smooth Muscle Phasic Contraction. The Journal of Membrane Biology, 198(2), pp. 95-101. Springer-Verlag 10.1007/s00232-004-0663-1
2003
Monastyrskaya, K.; Babiychuk, E. B.; Schittny, J. C.; Rescher, U.; Gerke, V.; Mannherz, H.-G.; Draeger, A. (2003). The expression levels of three raft-associated molecules in cultivated vascular cells are dependent on culture conditions. Cellular and molecular life sciences, 60(12), pp. 2702-2709. Birkhäuser-Verlag 10.1007/s00018-003-3307-1
